This study explored the real-world effectiveness of the Diabefly® DTx program in improving glycemic control and reducing weight among 205 participants with T2D. At the end of the 90 days program, a significant mean reduction in HbA1c, weight, BMI and waist circumference by 1.6%, 2.4kg, 0.8 kg/m2, and 3.5cm was observed respectively. 87.8% participants reduced their HbA1c levls by >1%, while 68.29% reduced weight by > 5kg. In conclusion, a significant improvement in glycemic control and reduction in weight and BMI was observed after participation in Diabefly® program.