Understanding personalized glycemic response (PGR) among 108 participants through the Diabefly® program, led to significant reduction in mean calorie, carbohydrate and fat intake by 9.34%, 10.44%, and 7.95% respectively. Mean energy attributed from protein significantly increased by 10.36%. 66 participants reduced their weight, BMI, and HbA1c by 3.41kg, 1.16kg/m2, and 2.02% respectively, while 42 participants reduced their waist circumference by 4.85cm. These results suggests the potential of understanding PGR in an effective manner through the Diabefly® program for improved outcomes.