Lifestyle management and behavioral modification is an integral aspect for the effective prevention and management of type 2 diabetes mellitus (T2D). Current study analysed the effectiveness of personalized glycemic response based Diabefly-Pro digital therapeutics program among 64 participants with T2D for better glycemic control. Out of all the participants, mean blood glucose, and time-above-range was significantly reduced by 17.5 mg/dL, 11% respectively, while the time in range significantly improved by 4.5%. Personalized glycemic response-based Diabefly-Pro digital therapeutics program was effective in achieving better glycemic control in people with T2D