Higher diabetes distress is associated with poor glycemic control and compromised diabetes self-care. Hence, this study investigated the real-world effectiveness of virtual psychotherapy on the distress levels and HbA1c of 43 patients with Type 2 diabetes and revealed that post intervention, distress scores decreased by 22.0 % from baseline 1.55 and HbA1c levels reduced by 1.74 % from baseline 1.72. Thus, the study showed that the Diabefly® DTx program can help in better management of diabetes